Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ SUMOylation Inhibitor III, 2-D08
A cell-permeable compound that prevents the transfer of SUMO from the E2 thioester to the substrate without affecting SUMO-activating enzyme E1 (SAE-1/2) or E2 Ubc9-SUMO thioester formation.
MilliporeSigma™ Calbiochem™ E-Cadherin Upregulator, ResEcad
A cell-permeable isoxazolocarboxamide compound that enhances the E-cadherin protein level in lung squamous cell carcinoma H520 and colorectal adenocarcinoma SW620 cells.
MilliporeSigma™ Calbiochem™ PI 3-Kγ Inhibitor
The PI 3-Kγ Inhibitor, also referenced under CAS 648450-29-7, controls the biological activity of PI 3-Kγ. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ 4-Cyano-3-methylisoquinoline
A potent, cell-permeable, reversible, and specific inhibitor of protein kinase A (IC50 = 30 nM).
MilliporeSigma™ Calbiochem™ Cinnabarinic acid
A partial, low-potency agonist highly selective for mGlu4 receptors (EC50 > 100μM, no effect on other mGlu subtype rece
MilliporeSigma™ Calbiochem™ Brevetoxin PbTx-3, Ptychodiscus brevis
Lipid-soluble polyether marine toxin produced by the red tide dinoflagellate, Ptychodiscus brevis, found along the Gulf Coast of Florida.
MilliporeSigma™ Calbiochem™ InSolution™ Fluvastatin, Sodium Salt
A synthetic, competitive inhibitor of HMG-CoA reductase that acts as anti-hypercholesterolemic agent.
MilliporeSigma™ Calbiochem™ Caspase Modulator II, 1541B
Caspase Modulator II, 1541B primarily used in Inhibition.
MilliporeSigma™ Calbiochem™ CL316243 Hydrate
A very potent agonist highly selective for β3 adrenoceptors (EC50 =
MilliporeSigma™ Calbiochem™ KN-92
KN-92, CAS 1135280-28-2, is useful as a negative control for KN-93 (Cat. No. 422708), a Ca2+/CaM Kinase II inhibitor.
MilliporeSigma™ Calbiochem™ USP1-UAF1 Inhibitor, ML323
A cell-permeable, selective, potent, and reversible inhibitor of USP1-UAF1 deubiquitinase (IC50 = 76 nM in Ub-Rhodamine based assays). Does not disrupt USP1-UAF1 association.
MilliporeSigma™ Calbiochem™ IκB Kinase Inactive Control Peptide, Cell-Permeable
An inactive control for IκB Kinase Inhibitor Peptide.
MilliporeSigma™ Calbiochem™ Cilostamide
A cell-permeable selective inhibitor of cGMP-inhibited phosphodiesterase (PDE III; IC50 = 70 nM).
MilliporeSigma™ Calbiochem™ Caspase-6 Substrate III, Fluorogenic
A fluorogenic substrate for caspase-6 (Mch2).
MilliporeSigma™ Calbiochem™ Mer RTK Inhibitor, UNC569
The Mer RTK Inhibitor, UNC569 controls the biological activity of Mer RTK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.